I make a donation
objectif
Systematic detection of polyvascular disease combined with aggressive secondary prevention in patients presenting with severe coronary artery disease.
date de réalisation
2007
nombre de patients
521
nombre de centres participants
25 centers in France
type de financement
Public (APHP & Institute of Atherothrombosis)
Référence
NCT00445835
Active Detection and Management of the Extension of Atherothrombosis in High Risk Coronary Patients In Comparison With Standard of Care for Coronary Atherosclerosis : The AMERICA Study
Coronary artery disease is the first cause of death related to atherothrombosis. There is a close correlation between the extension of coronary artery disease and the severity of atherosclerotic lesions in extra coronary arterial beds. In addition, these symptomatic extracoronary lesions dramatically decrease the survival of these patients. However, scant data are available regarding the prevalence of extracoronary asymptomatic lesions. Conversely, the annual absolute risk of these lesions remains unknown. Consequently, whether a systematic identification of these extracoronary asymptomatic lesions is relevant remains to be established.
The Primary Objective and Primary Endpoint of the AMERICA study is to demonstrate the superiority of an active detection and management of the extension of atherothrombosis in high Risk coronary patients (active strategy) in comparison with standard of care for coronary atherosclerosis (conservative strategy).
source clinicaltrials.gov
Publication
Présentation
En cours
En cours
En cours