Centralized analyses

Platelet function test

Thanks to its numerous analysis devices (optical aggregometer, Multiplate® analyzer, VerifyNow® system, flow cytometer, ELISA, ROTEM®, TEG® plate reader) and in partnership with the INSERM UMRS 1166 unit, the ACTION Group is able to perform various analyses evaluating platelet reactivity.

• Measurement of platelet aggregation ;
• Coagulation factor analysis ;
• Receptor expression with measurement of surface proteins ;
• Efficacy measurement of anti-platelet treatment ;
• Measurement of platelet activation under drug treatments ;
• Measurement of the response variability.

Related studies: ARCTIC – ANTARCTIC – Private ATLANTIC – AMPHORE – GAMMA – GIANT

Genetics

Through DNA analysis systems (Spartan Rx® and Verigene®) the ACTION Group, in partnership with the INSERM UMRS 1166 unit, offers to determine the genetic profiles of patients.

• Identification of genetic variants resistant to anti-platelets ;
• Genes predictive of stent thrombosis ;
• Therapeutic adaptation according to the genetic profile ;
• Fibrinolysis interaction.

Related studies: ARCTIC-GENE, GIANT, ONASSIST, AMPHORE, GAMMA

Thrombus analysis

• Structure of the blood clot : physiopathology and pharmacology ;
• Thrombus biology (Transcriptome) ;
• Thrombus imaging ;
• Developing and analysis of fibrine clot (density, lyse speed).

Related studies : TIDE, AERE DILATE, PEPCIT

Medical imaging

The ACTION team gathers medical experts and specially trained personnel, and as a result is able to offer diverse solutions for the analysis of medical imaging.

• Coronary angiography (TIMI flow, cTFC, TMPG, SYNTAX score, ACC/AHA classification of coronary lesions, etc.) ;
• CT Scanner ;
• Echography ;
• Feasability, training and assistance to centers.

Related trials: ATOLL, EVA-MI, ATLANTIC, ARCTIC, CULPRIT-SHOCK, ALPHEUS