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STEEPLE

To evaluating the impact of IV enoxaparine against HNF in elective angioplasty

Terminée

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objectif

Hematomas of at least 5 cm and outcomes in patients undergoing elective percutaneous coronary intervention: insights from the SafeTy and Efficacy of Enoxaparin in PCI patients.

date de réalisation

2004

nombre de patients

3528

nombre de centres participants

129 centers in 29 countries

type de financement

Private (Sanofi-Aventis)

Référence

NCT00077844

Safety and Efficacy of Enoxaparin in Percutaneous Coronary Intervention (PCI) Patients, an International Randomized Evaluation (STEEPLE)

Study Description

The purpose of this study is to evaluate the efficacy and safety of intravenous enoxaparin versus intravenous unfractionated heparin (UFH) in patients undergoing non-emergent PCI, as assessed by measuring the incidence of non-coronary artery bypass graft (CABG) major and minor bleeding.

source clinicaltrials.gov

Publications

  • Enoxaparin versus unfractionated heparin in elective percutaneous coronary intervention
    Gilles Montalescot, Harvey D White, Richard Gallo, Marc Cohen, P Gabriel Steg, Philip E G Aylward, Christoph Bode, Massimo Chiariello, Spencer B King 3rd, Robert A Harrington, Walter J Desmet, Carlos Macaya, Steven R Steinhubl, STEEPLE Investigators
    Publicated in The New England Journal of Medecine
  • Impact of anticoagulation levels on outcomes in patients undergoing elective percutaneous coronary intervention: insights from the STEEPLE trial
    Gilles Montalescot, Marc Cohen, Genevieve Salette, Walter J Desmet, Carlos Macaya, Philip E G Aylward, Ph Gabriel Steg, Harvey D White, Richard Gallo, Steven R Steinhubl, STEEPLE Investigators
    Publicated in European Heart Journal

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